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Lipid profiling of C. elegans strains administered pro-longevity drugs and drug combinations

We report the effect of four lifespan modifying drugs and of synergistic combinations of these drugs on lipid profile in Caenorhabditis elegans. We employ ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS) to compare the abundance of lipid species in treated and control animal...

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Detalles Bibliográficos
Autores principales: Admasu, Tesfahun Dessale, Batchu, Krishna Chaithanya, Ng, Li Fang, Cazenave-Gassiot, Amaury, Wenk, Markus R., Gruber, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198751/
https://www.ncbi.nlm.nih.gov/pubmed/30351306
http://dx.doi.org/10.1038/sdata.2018.231