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Combining probabilistic alignments with read pair information improves accuracy of split-alignments
MOTIVATION: Split-alignments provide base-pair-resolution evidence of genomic rearrangements. In practice, they are found by first computing high-scoring local alignments, parts of which are then combined into a split-alignment. This approach is challenging when aligning a short read to a large and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198854/ https://www.ncbi.nlm.nih.gov/pubmed/29790902 http://dx.doi.org/10.1093/bioinformatics/bty398 |