Zileuton suppresses cholangiocarcinoma cell proliferation and migration through inhibition of the Akt signaling pathway

BACKGROUND: Inflammatory lipid mediators play an important role in several cancer types. Leukotrienes (LTs), pro-inflammatory lipid mediators, are involved in chronic inflammation and cancer progression. They are derived from arachidonic acid by 5-lipoxygenase (5-LOX) activity. On the other hand, 15...

Descripción completa

Detalles Bibliográficos
Autores principales: Khophai, Sasikamon, Thanee, Malinee, Techasen, Anchalee, Namwat, Nisana, Klanrit, Poramate, Titapun, Attapol, Jarearnrat, Apiwat, Sa-Ngiamwibool, Prakasit, Loilome, Watcharin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198876/
https://www.ncbi.nlm.nih.gov/pubmed/30410359
http://dx.doi.org/10.2147/OTT.S178942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198876/
https://www.ncbi.nlm.nih.gov/pubmed/30410359
http://dx.doi.org/10.2147/OTT.S178942

Ejemplares similares