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Zileuton suppresses cholangiocarcinoma cell proliferation and migration through inhibition of the Akt signaling pathway

BACKGROUND: Inflammatory lipid mediators play an important role in several cancer types. Leukotrienes (LTs), pro-inflammatory lipid mediators, are involved in chronic inflammation and cancer progression. They are derived from arachidonic acid by 5-lipoxygenase (5-LOX) activity. On the other hand, 15...

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Detalles Bibliográficos
Autores principales:	Khophai, Sasikamon, Thanee, Malinee, Techasen, Anchalee, Namwat, Nisana, Klanrit, Poramate, Titapun, Attapol, Jarearnrat, Apiwat, Sa-Ngiamwibool, Prakasit, Loilome, Watcharin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198876/ https://www.ncbi.nlm.nih.gov/pubmed/30410359 http://dx.doi.org/10.2147/OTT.S178942

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