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Personalized nanomedicine: a rapid, sensitive, and selective UV–vis spectrophotometry method for the quantification of nanostructured PEG-asparaginase activity in children’s plasma

PURPOSE: PEGylated asparaginase (PEG-ASNase), which hydrolyzes asparagine to ammonia and aspartic acid, is an effective nanostructured antitumor agent for acute lymphoblastic leukemia (ALL). In order to monitor the activity of PEG-ASNase in plasma and design an individualization project, a rapid and...

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Wang, Yongren, Wang, Ru, Shen, Yan, Xu, Jing, Webster, Thomas J, Fang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198885/
https://www.ncbi.nlm.nih.gov/pubmed/30410325
http://dx.doi.org/10.2147/IJN.S167380