Cargando…

BDNF rs6265 polymorphism methylation in Multiple Sclerosis: A possible marker of disease progression

INTRODUCTION: Brain-Derived Neurotrophic Factor (BDNF) and its most common polymorphism Val66Met are known to have a role in Multiple Sclerosis (MS) pathogenesis. Evidence is accumulating that there is an involvement of DNA methylation in the regulation of BDNF expression. The aim of this study was...

Descripción completa

Detalles Bibliográficos
Autores principales: Nociti, Viviana, Santoro, Massimo, Quaranta, Davide, Losavio, Francesco Antonio, De Fino, Chiara, Giordano, Rocco, Palomba, Nicole, Rossini, Paolo Maria, Guerini, Franca Rosa, Clerici, Mario, Caputo, Domenico, Mirabella, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198951/
https://www.ncbi.nlm.nih.gov/pubmed/30352103
http://dx.doi.org/10.1371/journal.pone.0206140