Metabolic reprogramming by Dichloroacetic acid potentiates photodynamic therapy of human breast adenocarcinoma MCF-7 cells

Aberrant glycolytic metabolism is one of the hallmarks of carcinogenesis and therefore reversal of metabolic transformation is a promising drug target in cancer treatment strategies. Dichloroacetic acid (DCA) is known to target the glycolytic pathway in cancer cells and facilitates reversal of metab...

Descripción completa

Detalles Bibliográficos
Autores principales: Alkarakooly, Zeiyad, Al-Anbaky, Qudes A., Kannan, Krishnaswamy, Ali, Nawab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198976/
https://www.ncbi.nlm.nih.gov/pubmed/30352078
http://dx.doi.org/10.1371/journal.pone.0206182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198976/
https://www.ncbi.nlm.nih.gov/pubmed/30352078
http://dx.doi.org/10.1371/journal.pone.0206182

Ejemplares similares