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Metabolic reprogramming by Dichloroacetic acid potentiates photodynamic therapy of human breast adenocarcinoma MCF-7 cells

Aberrant glycolytic metabolism is one of the hallmarks of carcinogenesis and therefore reversal of metabolic transformation is a promising drug target in cancer treatment strategies. Dichloroacetic acid (DCA) is known to target the glycolytic pathway in cancer cells and facilitates reversal of metab...

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Detalles Bibliográficos
Autores principales:	Alkarakooly, Zeiyad, Al-Anbaky, Qudes A., Kannan, Krishnaswamy, Ali, Nawab
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198976/ https://www.ncbi.nlm.nih.gov/pubmed/30352078 http://dx.doi.org/10.1371/journal.pone.0206182

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