CARD domain of rat RIP2 kinase: Refolding, solution structure, pH-dependent behavior and protein-protein interactions

RIP2, one of the RIP kinases, interacts with p75 neurotrophin receptor, regulating the neuron survival, and with NOD1 and NOD2 proteins, causing the innate immune response against gram-negative and gram-positive bacteria via its caspase recruitment domain (CARD). This makes RIP2 a prospective target...

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Detalles Bibliográficos
Autores principales: Goncharuk, Sergey A., Artemieva, Lilya E., Tabakmakher, Valentin M., Arseniev, Alexander S., Mineev, Konstantin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198988/
https://www.ncbi.nlm.nih.gov/pubmed/30352081
http://dx.doi.org/10.1371/journal.pone.0206244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198988/
https://www.ncbi.nlm.nih.gov/pubmed/30352081
http://dx.doi.org/10.1371/journal.pone.0206244

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