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Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk

Although numerous genetic loci have been associated with coronary artery disease (CAD) with genome wide association studies, efforts are needed to identify the causal genes in these loci and link them into fundamental signaling pathways. Recent studies have investigated the disease mechanism of CAD...

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Detalles Bibliográficos
Autores principales: Iyer, Dharini, Zhao, Quanyi, Wirka, Robert, Naravane, Ameay, Nguyen, Trieu, Liu, Boxiang, Nagao, Manabu, Cheng, Paul, Miller, Clint L., Kim, Juyong Brian, Pjanic, Milos, Quertermous, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198989/
https://www.ncbi.nlm.nih.gov/pubmed/30307970
http://dx.doi.org/10.1371/journal.pgen.1007681