Identifying EGFR-Expressed Cells and Detecting EGFR Multi-Mutations at Single-Cell Level by Microfluidic Chip

EGFR mutations companion diagnostics have been proved to be crucial for the efficacy of tyrosine kinase inhibitor targeted cancer therapies. To uncover multiple mutations occurred in minority of EGFR-mutated cells, which may be covered by the noises from majority of un-mutated cells, is currently be...

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Detalles Bibliográficos
Autores principales: Li, Ren, Zhou, Mingxing, Li, Jine, Wang, Zihua, Zhang, Weikai, Yue, Chunyan, Ma, Yan, Peng, Hailin, Wei, Zewen, Hu, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199061/
https://www.ncbi.nlm.nih.gov/pubmed/30393665
http://dx.doi.org/10.1007/s40820-017-0168-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199061/
https://www.ncbi.nlm.nih.gov/pubmed/30393665
http://dx.doi.org/10.1007/s40820-017-0168-y

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