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Quantification of gene expression patterns to reveal the origins of abnormal morphogenesis

The earliest developmental origins of dysmorphologies are poorly understood in many congenital diseases. They often remain elusive because the first signs of genetic misregulation may initiate as subtle changes in gene expression, which are hard to detect and can be obscured later in development by...

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Detalles Bibliográficos
Autores principales: Martínez-Abadías, Neus, Mateu Estivill, Roger, Sastre Tomas, Jaume, Motch Perrine, Susan, Yoon, Melissa, Robert-Moreno, Alexandre, Swoger, Jim, Russo, Lucia, Kawasaki, Kazuhiko, Richtsmeier, Joan, Sharpe, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199133/
https://www.ncbi.nlm.nih.gov/pubmed/30234486
http://dx.doi.org/10.7554/eLife.36405