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Development and evaluation of a rapid analysis for HEPES determination in (68)Ga-radiotracers

BACKGROUND: HEPES is a favorable buffer for (68)Ga-complexations in radiochemical laboratories. The drawback of this buffer is its prescribed limit of 200 μg per recommended application volume in the final formulation. Currently, a TLC test according to the European Pharmacopoeia (Ph. Eur.) has to b...

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Detalles Bibliográficos
Autores principales: Pfaff, Sarah, Nehring, Tina, Pichler, Verena, Cardinale, Jens, Mitterhauser, Markus, Hacker, Marcus, Wadsak, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199202/
https://www.ncbi.nlm.nih.gov/pubmed/30353250
http://dx.doi.org/10.1186/s13550-018-0449-6