pH and redox dual-responsive copolymer micelles with surface charge reversal for co-delivery of all-trans-retinoic acid and paclitaxel for cancer combination chemotherapy

BACKGROUND: Co-delivery all-trans-retinoic acid (ATRA) and paclitaxel (PTX) is an effective strategy for cancer therapy. However, in many previous reported ATRA conjugated co-delivery systems, the ATRA was released slower than PTX, and the total drug release of ATRA far lower than that of PTX. PURPO...

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Detalles Bibliográficos
Autores principales: Zhang, Yanqiu, Peng, Lianjun, Chu, Jiahui, Zhang, Ming, Sun, Lizhu, Zhong, Bin, Wu, Qiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199233/
https://www.ncbi.nlm.nih.gov/pubmed/30410335
http://dx.doi.org/10.2147/IJN.S179046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199233/
https://www.ncbi.nlm.nih.gov/pubmed/30410335
http://dx.doi.org/10.2147/IJN.S179046

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