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pH and redox dual-responsive copolymer micelles with surface charge reversal for co-delivery of all-trans-retinoic acid and paclitaxel for cancer combination chemotherapy

BACKGROUND: Co-delivery all-trans-retinoic acid (ATRA) and paclitaxel (PTX) is an effective strategy for cancer therapy. However, in many previous reported ATRA conjugated co-delivery systems, the ATRA was released slower than PTX, and the total drug release of ATRA far lower than that of PTX. PURPO...

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Detalles Bibliográficos
Autores principales:	Zhang, Yanqiu, Peng, Lianjun, Chu, Jiahui, Zhang, Ming, Sun, Lizhu, Zhong, Bin, Wu, Qiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199233/ https://www.ncbi.nlm.nih.gov/pubmed/30410335 http://dx.doi.org/10.2147/IJN.S179046

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