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IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid Model

BACKGROUND & AIMS: Crohn’s disease is an inflammatory bowel disease that affects the ileum and is associated with increased cytokines. Although interleukin (IL)6, IL17, IL21, and IL22 are increased in Crohn’s disease and are associated with disrupted epithelial regeneration, little is known abou...

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Detalles Bibliográficos
Autores principales: Zwarycz, Bailey, Gracz, Adam D., Rivera, Kristina R., Williamson, Ian A., Samsa, Leigh A., Starmer, Josh, Daniele, Michael A., Salter-Cid, Luisa, Zhao, Qihong, Magness, Scott T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199238/
https://www.ncbi.nlm.nih.gov/pubmed/30364840
http://dx.doi.org/10.1016/j.jcmgh.2018.06.008