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IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid Model
BACKGROUND & AIMS: Crohn’s disease is an inflammatory bowel disease that affects the ileum and is associated with increased cytokines. Although interleukin (IL)6, IL17, IL21, and IL22 are increased in Crohn’s disease and are associated with disrupted epithelial regeneration, little is known abou...
Autores principales: | Zwarycz, Bailey, Gracz, Adam D., Rivera, Kristina R., Williamson, Ian A., Samsa, Leigh A., Starmer, Josh, Daniele, Michael A., Salter-Cid, Luisa, Zhao, Qihong, Magness, Scott T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199238/ https://www.ncbi.nlm.nih.gov/pubmed/30364840 http://dx.doi.org/10.1016/j.jcmgh.2018.06.008 |
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