c-Fos induces chondrogenic tumor formation in immortalized human mesenchymal progenitor cells

Mesenchymal progenitor cells (MPCs) have been hypothesized as cells of origin for sarcomas, and c-Fos transcription factor has been showed to act as an oncogene in bone tumors. In this study, we show c-Fos is present in most sarcomas with chondral phenotype, while multiple other genes are related to...

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Detalles Bibliográficos
Autores principales: Abarrategi, Ander, Gambera, Stefano, Alfranca, Arantzazu, Rodriguez-Milla, Miguel A., Perez-Tavarez, Raquel, Rouault-Pierre, Kevin, Waclawiczek, Alexander, Chakravarty, Probir, Mulero, Francisca, Trigueros, César, Navarro, Samuel, Bonnet, Dominique, García-Castro, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199246/
https://www.ncbi.nlm.nih.gov/pubmed/30353072
http://dx.doi.org/10.1038/s41598-018-33689-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199246/
https://www.ncbi.nlm.nih.gov/pubmed/30353072
http://dx.doi.org/10.1038/s41598-018-33689-0

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