Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of the PI3K/Akt/GSK-3β signalling pathway in oral cancer

Of late, nimbolide, a limonoid from the neem tree (Azadirachta indica) has gained increasing research attention owing to its potent antiproliferative and apoptosis-inducing effects. The present study was designed to investigate the effect of nimbolide on autophagy and the time point at which the pho...

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Detalles Bibliográficos
Autores principales: Sophia, Josephraj, Kowshik, Jaganathan, Dwivedi, Anju, Bhutia, Sujit K, Manavathi, Bramanandam, Mishra, Rajakishore, Nagini, Siddavaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199248/
https://www.ncbi.nlm.nih.gov/pubmed/30352996
http://dx.doi.org/10.1038/s41419-018-1126-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199248/
https://www.ncbi.nlm.nih.gov/pubmed/30352996
http://dx.doi.org/10.1038/s41419-018-1126-4

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