Ionic and cellular mechanisms underlying TBX5/PITX2 insufficiency-induced atrial fibrillation: Insights from mathematical models of human atrial cells

Transcription factors TBX5 and PITX2 involve in the regulation of gene expression of ion channels and are closely associated with atrial fibrillation (AF), the most common cardiac arrhythmia in developed countries. The exact cellular and molecular mechanisms underlying the increased susceptibility t...

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Detalles Bibliográficos
Autores principales: Bai, Jieyun, Gladding, Patrick A., Stiles, Martin K., Fedorov, Vadim V., Zhao, Jichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199257/
https://www.ncbi.nlm.nih.gov/pubmed/30353147
http://dx.doi.org/10.1038/s41598-018-33958-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199257/
https://www.ncbi.nlm.nih.gov/pubmed/30353147
http://dx.doi.org/10.1038/s41598-018-33958-y

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