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A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers

Peripheral nerves are anisotropic and heterogeneous neural tissues. Their complex physiology restricts realistic in vitro models, and high resolution and selective probing of axonal activity. Here, we present a nerve-on-a-chip platform that enables rapid extracellular recording and axonal tracking o...

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Detalles Bibliográficos
Autores principales: Gribi, Sandra, du Bois de Dunilac, Sophie, Ghezzi, Diego, Lacour, Stéphanie P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199302/
https://www.ncbi.nlm.nih.gov/pubmed/30353009
http://dx.doi.org/10.1038/s41467-018-06895-7