Developmental protein kinase C hyper-activation results in microcephaly and behavioral abnormalities in zebrafish

Susceptible genetic polymorphisms and altered expression levels of protein kinase C (PKC)-encoding genes suggest overactivation of PKC in autism spectrum disorder (ASD) development. To delineate the pathological role of PKC, we pharmacologically stimulated its activity during the early development o...

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Detalles Bibliográficos
Autores principales: Liu, Taian, Shi, Yujian, Chan, Matthew T. V., Peng, Gang, Zhang, Quan, Sun, Xiao, Zhu, Zeyao, Xie, Yuxin, Sham, Kathy W. Y., Li, Jianzhen, Liu, Xiaodong, Ho, Idy H. T., Gin, Tony, Lu, Zhonghua, Wu, William K. K., Cheng, Christopher H. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199330/
https://www.ncbi.nlm.nih.gov/pubmed/30352990
http://dx.doi.org/10.1038/s41398-018-0285-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199330/
https://www.ncbi.nlm.nih.gov/pubmed/30352990
http://dx.doi.org/10.1038/s41398-018-0285-5

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