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The Effect of Hypoxia and Metformin on Fatty Acid Uptake, Storage, and Oxidation in L6 Differentiated Myotubes

Metabolic impairments associated with obstructive sleep apnea syndrome (OSA) are linked to tissue hypoxia, however, the explanatory molecular and endocrine mechanisms remain unknown. Using gas-permeable cultureware, we studied the chronic effects of mild and severe hypoxia on free fatty acid (FFA) u...

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Detalles Bibliográficos
Autores principales: Musutova, Martina, Elkalaf, Moustafa, Klubickova, Natalie, Koc, Michal, Povysil, Stanislav, Rambousek, Jan, Volckaert, Beatriz, Duska, Frantisek, Trinh, Minh Duc, Kalous, Martin, Trnka, Jan, Balusikova, Kamila, Kovar, Jan, Polak, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199370/
https://www.ncbi.nlm.nih.gov/pubmed/30386299
http://dx.doi.org/10.3389/fendo.2018.00616