Convergent Metabotropic Signaling Pathways Inhibit SK Channels to Promote Synaptic Plasticity in the Hippocampus

Hebbian synaptic plasticity at hippocampal Schaffer collateral synapses is tightly regulated by postsynaptic small conductance (SK) channels that restrict NMDA receptor activity. SK channels are themselves modulated by G-protein-coupled signaling pathways, but it is not clear under what conditions t...

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Detalles Bibliográficos
Autores principales: Tigaret, Cezar M., Chamberlain, Sophie E.L., Sadowski, Joseph H.L.P., Hall, Jeremy, Ashby, Michael C., Mellor, Jack R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199408/
https://www.ncbi.nlm.nih.gov/pubmed/30242046
http://dx.doi.org/10.1523/JNEUROSCI.1160-18.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199408/
https://www.ncbi.nlm.nih.gov/pubmed/30242046
http://dx.doi.org/10.1523/JNEUROSCI.1160-18.2018

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