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Convergent Metabotropic Signaling Pathways Inhibit SK Channels to Promote Synaptic Plasticity in the Hippocampus
Hebbian synaptic plasticity at hippocampal Schaffer collateral synapses is tightly regulated by postsynaptic small conductance (SK) channels that restrict NMDA receptor activity. SK channels are themselves modulated by G-protein-coupled signaling pathways, but it is not clear under what conditions t...
Autores principales: | Tigaret, Cezar M., Chamberlain, Sophie E.L., Sadowski, Joseph H.L.P., Hall, Jeremy, Ashby, Michael C., Mellor, Jack R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199408/ https://www.ncbi.nlm.nih.gov/pubmed/30242046 http://dx.doi.org/10.1523/JNEUROSCI.1160-18.2018 |
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