HIV-1 Vpr Reprograms CLR4(DCAF1) E3 Ubiquitin Ligase to Antagonize Exonuclease 1-Mediated Restriction of HIV-1 Infection

Viral accessory proteins hijack host cell E3 ubiquitin ligases to antagonize innate/intrinsic defenses and thereby provide a more permissive environment for virus replication. Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr reprograms CRL4(DCAF1) E3 to antagonize select postreplica...

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Detalles Bibliográficos
Autores principales: Yan, Junpeng, Shun, Ming-Chieh, Hao, Caili, Zhang, Yi, Qian, Juan, Hrecka, Kasia, DeLucia, Maria, Monnie, Christina, Ahn, Jinwoo, Skowronski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199497/
https://www.ncbi.nlm.nih.gov/pubmed/30352932
http://dx.doi.org/10.1128/mBio.01732-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199497/
https://www.ncbi.nlm.nih.gov/pubmed/30352932
http://dx.doi.org/10.1128/mBio.01732-18

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