Glucose Controls the Expression of Polypyrimidine Tract-Binding Protein 1 via the Insulin Receptor Signaling Pathway in Pancreatic β Cells

In pancreatic β cells, glucose stimulates the biosynthesis of insulin at transcriptional and post-transcriptional levels. The RNA-binding protein, polypyrimidine tract-binding protein 1 (PTBP1), also named hnRNP I, acts as a critical mediator of insulin biosynthesis through binding to the pyrimidine...

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Detalles Bibliográficos
Autores principales: Jeong, Da Eun, Heo, Sungeun, Han, Ji Hye, Lee, Eun-young, Kulkarni, Rohit N., Kim, Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199568/
https://www.ncbi.nlm.nih.gov/pubmed/30165730
http://dx.doi.org/10.14348/molcells.2018.0147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199568/
https://www.ncbi.nlm.nih.gov/pubmed/30165730
http://dx.doi.org/10.14348/molcells.2018.0147

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