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Glucose Controls the Expression of Polypyrimidine Tract-Binding Protein 1 via the Insulin Receptor Signaling Pathway in Pancreatic β Cells

In pancreatic β cells, glucose stimulates the biosynthesis of insulin at transcriptional and post-transcriptional levels. The RNA-binding protein, polypyrimidine tract-binding protein 1 (PTBP1), also named hnRNP I, acts as a critical mediator of insulin biosynthesis through binding to the pyrimidine...

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Detalles Bibliográficos
Autores principales:	Jeong, Da Eun, Heo, Sungeun, Han, Ji Hye, Lee, Eun-young, Kulkarni, Rohit N., Kim, Wook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199568/ https://www.ncbi.nlm.nih.gov/pubmed/30165730 http://dx.doi.org/10.14348/molcells.2018.0147

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