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Toward the Total Synthesis of Ryanodol via Oxidative Alkyne–1,3-Diketone Annulation: Construction of a Ryanoid Tetracycle

[Image: see text] A synthetic strategy conceived with the intent of establishing a novel approach to the de novo construction of ryanoids is described that is based on a recently developed metallacycle-mediated intramolecular oxidative alkyne–1,3-diketone coupling reaction. In short, a one-pot annul...

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Detalles Bibliográficos
Autores principales: Du, Kang, Kier, Matthew J., Rheingold, Arnold L., Micalizio, Glenn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199674/
https://www.ncbi.nlm.nih.gov/pubmed/30264570
http://dx.doi.org/10.1021/acs.orglett.8b02767