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A diversity-generating retroelement encoded by a globally ubiquitous Bacteroides phage

BACKGROUND: Diversity-generating retroelements (DGRs) are genetic cassettes that selectively mutate target genes to produce hypervariable proteins. First characterized in Bordetella bacteriophage BPP-1, the DGR creates a hypervariable phage tail fiber that enables host tropism switching. Subsequent...

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Detalles Bibliográficos
Autores principales: Benler, Sean, Cobián-Güemes, Ana Georgina, McNair, Katelyn, Hung, Shr-Hau, Levi, Kyle, Edwards, Rob, Rohwer, Forest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199706/
https://www.ncbi.nlm.nih.gov/pubmed/30352623
http://dx.doi.org/10.1186/s40168-018-0573-6