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Co-expression of nuclear P38 and hormone receptors is prognostic of good long-term clinical outcome in primary breast cancer and is linked to upregulation of DNA repair

BACKGROUND: P38 mitogen activated protein kinase is an intermediary signal transduction factor with context-specific roles in breast cancer. Recent mechanistic studies add to the growing consensus that P38 is a tumour suppressor, and it may represent a novel target for breast cancer treatment. The a...

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Detalles Bibliográficos
Autores principales: Johnston, Simon J., Ahmad, Dena, Aleskandarany, Mohammed A., Kurozumi, Sasagu, Nolan, Chris C., Diez-Rodriguez, Maria, Green, Andrew R., Rakha, Emad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199714/
https://www.ncbi.nlm.nih.gov/pubmed/30352570
http://dx.doi.org/10.1186/s12885-018-4924-2