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MYC-Induced miR-203b-3p and miR-203a-3p Control Bcl-xL Expression and Paclitaxel Sensitivity in Tumor Cells()

Taxanes are chemotherapeutic agents used in the treatment of solid tumors, particularly of breast, ovarian, and lung origin. However, patients show divergent therapy responses, and the molecular determinants of taxane sensitivity have remained elusive. Especially the signaling pathways that promote...

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Detalles Bibliográficos
Autores principales: Aakko, Sofia, Straume, Anne Hege, Birkeland, Einar Elvbakken, Chen, Ping, Qiao, Xi, 'Lønning, Per Eystein', Kallio, Marko J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199766/
https://www.ncbi.nlm.nih.gov/pubmed/30359947
http://dx.doi.org/10.1016/j.tranon.2018.10.001