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Identification of growth-coupled production strains considering protein costs and kinetic variability
Conversion of renewable biomass to useful molecules in microbial cell factories can be approached in a rational and systematic manner using constraint-based reconstruction and analysis. Filtering for high confidence in silico designs is critical because in vivo construction and testing of strains is...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199775/ https://www.ncbi.nlm.nih.gov/pubmed/30370222 http://dx.doi.org/10.1016/j.mec.2018.e00080 |