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Staurosporine Induces the Generation of Polyploid Giant Cancer Cells in Non-Small-Cell Lung Carcinoma A549 Cells

Cultivation of A549 non-small-cell lung carcinoma (NSCLC) cells in the presence of staurosporine (SSP) leads to a reduction or a lack of proliferation in a concentration-dependent manner. This inhibition of proliferation is accompanied by the generation of polyploid giant cancer cells (PGCCs) that a...

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Detalles Bibliográficos
Autores principales: Glassmann, Alexander, Carrillo Garcia, Carmen, Janzen, Viktor, Kraus, Dominik, Veit, Nadine, Winter, Jochen, Probstmeier, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199859/
https://www.ncbi.nlm.nih.gov/pubmed/30406001
http://dx.doi.org/10.1155/2018/1754085