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Staurosporine Induces the Generation of Polyploid Giant Cancer Cells in Non-Small-Cell Lung Carcinoma A549 Cells
Cultivation of A549 non-small-cell lung carcinoma (NSCLC) cells in the presence of staurosporine (SSP) leads to a reduction or a lack of proliferation in a concentration-dependent manner. This inhibition of proliferation is accompanied by the generation of polyploid giant cancer cells (PGCCs) that a...
Autores principales: | Glassmann, Alexander, Carrillo Garcia, Carmen, Janzen, Viktor, Kraus, Dominik, Veit, Nadine, Winter, Jochen, Probstmeier, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199859/ https://www.ncbi.nlm.nih.gov/pubmed/30406001 http://dx.doi.org/10.1155/2018/1754085 |
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