Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy

For an activating immunotherapy such as adjuvants, a compound that can prolong immune stimulation may enhance efficacy. We leveraged data from two prior high throughput screens with NF-κB and interferon reporter cell lines to identify 4H-chromene-3-carbonitriles as a class of compounds that prolonge...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato-Kaneko, Fumi, Wang, Xiaodong, Yao, Shiyin, Hosoya, Tadashi, Lao, Fitzgerald S., Messer, Karen, Pu, Minya, Shukla, Nikunj M., Cottam, Howard B., Chan, Michael, Carson, Dennis A., Corr, Maripat, Hayashi, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199861/
https://www.ncbi.nlm.nih.gov/pubmed/30406141
http://dx.doi.org/10.1155/2018/8091283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199861/
https://www.ncbi.nlm.nih.gov/pubmed/30406141
http://dx.doi.org/10.1155/2018/8091283

Ejemplares similares