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Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy

For an activating immunotherapy such as adjuvants, a compound that can prolong immune stimulation may enhance efficacy. We leveraged data from two prior high throughput screens with NF-κB and interferon reporter cell lines to identify 4H-chromene-3-carbonitriles as a class of compounds that prolonge...

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Detalles Bibliográficos
Autores principales:	Sato-Kaneko, Fumi, Wang, Xiaodong, Yao, Shiyin, Hosoya, Tadashi, Lao, Fitzgerald S., Messer, Karen, Pu, Minya, Shukla, Nikunj M., Cottam, Howard B., Chan, Michael, Carson, Dennis A., Corr, Maripat, Hayashi, Tomoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199861/ https://www.ncbi.nlm.nih.gov/pubmed/30406141 http://dx.doi.org/10.1155/2018/8091283

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