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Zebularine Promotes Hepatic Differentiation of Rabbit Bone Marrow Mesenchymal Stem Cells by Interfering with p38 MAPK Signaling

Demethylating agent zebularine is reported to be capable of inducing differentiation of stem cells by activation of methylated genes, though its function in hepatocyte differentiation is unclear. p38 signal pathway is involved in differentiation of hepatocytes and regulating of DNA methyltransferase...

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Detalles Bibliográficos
Autores principales: Luo, Yong-Heng, Chen, Juan, Xiao, En-Hua, Li, Qiu-Yun, Luo, Yong-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199887/
https://www.ncbi.nlm.nih.gov/pubmed/30405726
http://dx.doi.org/10.1155/2018/9612512