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Animal models of amyotrophic lateral sclerosis: a comparison of model validity

Animal models are necessary to investigate the pathogenic features underlying motor neuron degeneration and for therapeutic development in amyotrophic lateral sclerosis (ALS). Measures of model validity allow for a critical interpretation of results from each model and caution from over-interpretati...

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Detalles Bibliográficos
Autores principales: Morrice, Jessica R., Gregory-Evans, Cheryl Y., Shaw, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199948/
https://www.ncbi.nlm.nih.gov/pubmed/30323119
http://dx.doi.org/10.4103/1673-5374.241445