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Novel EXO-T vaccine using polyclonal CD4(+) T cells armed with HER2-specific exosomes for HER2-positive breast cancer

Breast cancer is the leading cause of death in women globally. The human epidermal growth factor receptor 2 (HER2)-positive breast cancer is often associated with poor prognosis and high mortality. Even though anti-HER2 monoclonal antibodies have improved the clinical outcome, resistance to the anti...

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Detalles Bibliográficos
Autores principales: Li, Rong, Chibbar, Rajni, Xiang, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200095/
https://www.ncbi.nlm.nih.gov/pubmed/30410365
http://dx.doi.org/10.2147/OTT.S184898