Autophagy Controls CSL/RBPJκ Stability through a p62/SQSTM1-Dependent Mechanism

Cancer-associated fibroblasts (CAFs) are important at all tumor stages. CSL/RBPJκ suppresses the gene expression program leading to CAF activation and associated metabolic reprogramming, as well as autophagy. Little is known about CSL protein turnover, especially in the tumor microenvironment. We re...

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Detalles Bibliográficos
Autores principales: Goruppi, Sandro, Jo, Seung-Hee, Laszlo, Csaba, Clocchiatti, Andrea, Neel, Victor, Dotto, G. Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200139/
https://www.ncbi.nlm.nih.gov/pubmed/30231994
http://dx.doi.org/10.1016/j.celrep.2018.08.043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200139/
https://www.ncbi.nlm.nih.gov/pubmed/30231994
http://dx.doi.org/10.1016/j.celrep.2018.08.043

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