Cargando…
Autophagy Controls CSL/RBPJκ Stability through a p62/SQSTM1-Dependent Mechanism
Cancer-associated fibroblasts (CAFs) are important at all tumor stages. CSL/RBPJκ suppresses the gene expression program leading to CAF activation and associated metabolic reprogramming, as well as autophagy. Little is known about CSL protein turnover, especially in the tumor microenvironment. We re...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200139/ https://www.ncbi.nlm.nih.gov/pubmed/30231994 http://dx.doi.org/10.1016/j.celrep.2018.08.043 |