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The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner

Type 2 diabetes is typified by insulin-resistance in adipose tissue, skeletal muscle, and liver, leading to chronic hyperglycemia. Additionally, obesity and type 2 diabetes are characterized by chronic low-grade inflammation. Membrane-associated RING-CH-1 (MARCH1) is an E3 ubiquitin ligase best know...

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Detalles Bibliográficos
Autores principales: Bhagwandin, Candida, Ashbeck, Erin L., Whalen, Michael, Bandola-Simon, Joanna, Roche, Paul A., Szajman, Adam, Truong, Sarah Mai, Wertheim, Betsy C., Klimentidis, Yann C., Ishido, Satoshi, Renquist, Benjamin J., Lybarger, Lonnie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200199/
https://www.ncbi.nlm.nih.gov/pubmed/30356278
http://dx.doi.org/10.1371/journal.pone.0204898