Cargando…

The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner

Type 2 diabetes is typified by insulin-resistance in adipose tissue, skeletal muscle, and liver, leading to chronic hyperglycemia. Additionally, obesity and type 2 diabetes are characterized by chronic low-grade inflammation. Membrane-associated RING-CH-1 (MARCH1) is an E3 ubiquitin ligase best know...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhagwandin, Candida, Ashbeck, Erin L., Whalen, Michael, Bandola-Simon, Joanna, Roche, Paul A., Szajman, Adam, Truong, Sarah Mai, Wertheim, Betsy C., Klimentidis, Yann C., Ishido, Satoshi, Renquist, Benjamin J., Lybarger, Lonnie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200199/ https://www.ncbi.nlm.nih.gov/pubmed/30356278 http://dx.doi.org/10.1371/journal.pone.0204898

Ejemplares similares

Physiological substrates and ontogeny-specific expression of the ubiquitin ligases MARCH1 and MARCH8
por: Schriek, Patrick, et al.
Publicado: (2021)

Ubiquitination of HLA-DO by MARCH family E3 ligases
por: Jahnke, Martin, et al.
Publicado: (2013)

Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy
por: Zheng, Jun, et al.
Publicado: (2021)

Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3
por: Wang, Xiaoli, et al.
Publicado: (2007)

March1 E3 Ubiquitin Ligase Modulates Features of Allergic Asthma in an Ovalbumin-Induced Mouse Model of Lung Inflammation
por: Kishta, Osama A., et al.
Publicado: (2018)

Lack of the E3 Ubiquitin Ligase March1 Affects CD8 T Cell Fate and Exacerbates Insulin Resistance in Obese Mice
por: Majdoubi, Abdelilah, et al.
Publicado: (2020)

AIRE Functions As an E3 Ubiquitin Ligase
por: Uchida, Daisuke, et al.
Publicado: (2004)

Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection
por: Liu, Haiyin, et al.
Publicado: (2016)

Ubiquitin E3 ligase MARCH7 promotes ovarian tumor growth
por: Hu, Jianguo, et al.
Publicado: (2015)

Negative regulation of NEMO signaling by the ubiquitin E3 ligase MARCH2
por: Chathuranga, Kiramage, et al.
Publicado: (2020)

MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation
por: Eyster, Craig A., et al.
Publicado: (2011)

The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling
por: Yoo, Young-Suk, et al.
Publicado: (2015)

Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5
por: Merklinger, Lisa, et al.
Publicado: (2022)

Axotrophin/MARCH7 acts as an E3 ubiquitin ligase and ubiquitinates tau protein in vitro impairing microtubule binding
por: Flach, Katharina, et al.
Publicado: (2014)

Mitochondrial Ubiquitin Ligase MARCH5 Promotes TLR7 Signaling by Attenuating TANK Action
por: Shi, He-Xin, et al.
Publicado: (2011)

Increased expression of MARCH8, an E3 ubiquitin ligase, is associated with growth of esophageal tumor
por: Singh, Shivam, et al.
Publicado: (2017)

MARCH family E3 ubiquitin ligases selectively target and degrade cadherin family proteins
por: Seo, Tadahiko, et al.
Publicado: (2023)

Ubiquitin ligases and beyond
por: Dikic, Ivan, et al.
Publicado: (2012)

The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
por: Karbowski, Mariusz, et al.
Publicado: (2007)

Overview of Mitochondrial E3 Ubiquitin Ligase MITOL/MARCH5 from Molecular Mechanisms to Diseases
por: Shiiba, Isshin, et al.
Publicado: (2020)

Ubiquitination and Degradation of CFTR by the E3 Ubiquitin Ligase MARCH2 through Its Association with Adaptor Proteins CAL and STX6
por: Cheng, Jie, et al.
Publicado: (2013)

Mitochondria ubiquitin ligase, MARCH5 resolves hepatitis B virus X protein aggregates in the liver pathogenesis
por: Yoo, Young-Suk, et al.
Publicado: (2019)

Phenotypic and Genetic Characterization of Lower LDL Cholesterol and Increased Type 2 Diabetes Risk in the UK Biobank
por: Klimentidis, Yann C., et al.
Publicado: (2020)

Ubiquitin Ligases in Cholesterol Metabolism
por: Jiang, Wei, et al.
Publicado: (2014)

HERC Ubiquitin Ligases in Cancer
por: Sala-Gaston, Joan, et al.
Publicado: (2020)

MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway
por: Wilson, Kayla R., et al.
Publicado: (2018)

MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells
por: Oh, Jaehak, et al.
Publicado: (2013)

Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA
por: Subramanian, Aishwarya, et al.
Publicado: (2016)

Multi-Omics Reveals the Immunological Role and Prognostic Potential of Mitochondrial Ubiquitin Ligase MARCH5 in Human Breast Cancer
por: Chu, Pei-Yi, et al.
Publicado: (2021)

E3 Ubiquitin Ligase March1 Facilitates OX40L Expression in Allergen-Stimulated Dendritic Cells Through Mediating the Ubiquitination of HDAC11
por: Zhang, Xinxing, et al.
Publicado: (2021)

Mitochondrial ubiquitin ligase alleviates Alzheimer’s disease pathology via blocking the toxic amyloid-β oligomer generation
por: Takeda, Keisuke, et al.
Publicado: (2021)

The cholesterol synthesis enzyme lanosterol 14α-demethylase is post-translationally regulated by the E3 ubiquitin ligase MARCH6
por: Scott, Nicola A., et al.
Publicado: (2020)

Regulation of ubiquitin ligase dynamics by the nucleolus
por: Mekhail, Karim, et al.
Publicado: (2005)

Origin and Diversification of TRIM Ubiquitin Ligases
por: Marín, Ignacio
Publicado: (2012)

Evolution of Plant HECT Ubiquitin Ligases
por: Marín, Ignacio
Publicado: (2013)

The MARCH Family E3 Ubiquitin Ligase K5 Alters Monocyte Metabolism and Proliferation through Receptor Tyrosine Kinase Modulation
por: Karki, Roshan, et al.
Publicado: (2011)

The E3 ubiquitin ligase Itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner
por: Suryaraja, R, et al.
Publicado: (2013)

Smurf2 E3 ubiquitin ligase modulates proliferation and invasiveness of breast cancer cells in a CNKSR2 dependent manner
por: David, Diana, et al.
Publicado: (2014)

Signaling-mediated control of ubiquitin ligases in endocytosis
por: Polo, Simona
Publicado: (2012)

CRL Ubiquitin Ligases and DNA Damage Response
por: Li, Ju-Mei, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_omiudb14lh7dqo66afbskko6kr