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SETD2-dependent H3K36me3 plays a critical role in epigenetic regulation of the HPV31 life cycle

The life cycle of HPV is tied to the differentiation status of its host cell, with productive replication, late gene expression and virion production restricted to the uppermost layers of the stratified epithelium. HPV DNA is histone-associated, exhibiting a chromatin structure similar to that of th...

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Detalles Bibliográficos
Autores principales: Gautam, Dipendra, Johnson, Bryan A., Mac, Michelle, Moody, Cary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200281/
https://www.ncbi.nlm.nih.gov/pubmed/30312361
http://dx.doi.org/10.1371/journal.ppat.1007367