Biophysical models reveal the relative importance of transporter proteins and impermeant anions in chloride homeostasis

Fast synaptic inhibition in the nervous system depends on the transmembrane flux of Cl(-) ions based on the neuronal Cl(-) driving force. Established theories regarding the determinants of Cl(-) driving force have recently been questioned. Here, we present biophysical models of Cl(-) homeostasis usi...

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Detalles Bibliográficos
Autores principales: Düsterwald, Kira M, Currin, Christopher B, Burman, Richard J, Akerman, Colin J, Kay, Alan R, Raimondo, Joseph V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200395/
https://www.ncbi.nlm.nih.gov/pubmed/30260315
http://dx.doi.org/10.7554/eLife.39575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200395/
https://www.ncbi.nlm.nih.gov/pubmed/30260315
http://dx.doi.org/10.7554/eLife.39575

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