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Association of human leukocyte antigen alleles and supertypes with immunogenicity of oral rotavirus vaccine given to infants in China

Rotavirus (RV) vaccines show distinct immunogenicity in dozens of clinical trials, which is associated with multiple host and environmental factors. Previous research has demonstrated that the highly polymorphic human leukocyte antigen (HLA) system plays an essential role in regulating immune respon...

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Detalles Bibliográficos
Autores principales: Liu, Yueyue, Guo, Tai, Yu, Qingchuan, Zhang, Haowen, Du, Jialiang, Zhang, Yunqi, Xia, Shengli, Yang, Huan, Li, Qihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200448/
https://www.ncbi.nlm.nih.gov/pubmed/30290669
http://dx.doi.org/10.1097/MD.0000000000012706