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Expression-based analyses indicate a central role for hypoxia in driving tumor plasticity through microenvironment remodeling and chromosomal instability

Can transcriptomic alterations drive the evolution of tumors? We asked if changes in gene expression found in all patients arise earlier in tumor development and can be relevant to tumor progression. Our analyses of non-mutated genes from the non-amplified regions of the genome of 158 triple-negativ...

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Detalles Bibliográficos
Autores principales: Jing, Anqi, Vizeacoumar, Frederick S., Parameswaran, Sreejit, Haave, Bjorn, Cunningham, Chelsea E., Wu, Yuliang, Arnold, Roland, Bonham, Keith, Freywald, Andrew, Han, Jie, Vizeacoumar, Franco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200725/
https://www.ncbi.nlm.nih.gov/pubmed/30374409
http://dx.doi.org/10.1038/s41540-018-0074-z