Fisetin targets YB-1/RSK axis independent of its effect on ERK signaling: insights from in vitro and in vivo melanoma models

The anti-proliferative activity of dietary flavonoid fisetin has been validated in various cancer models. Establishing its precise mechanism of action has proved somewhat challenging given the multiplicity of its targets. We demonstrated that YB-1 promotes epithelial-to-mesenchymal transition and it...

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Detalles Bibliográficos
Autores principales: Sechi, Mario, Lall, Rahul K., Afolabi, Saheed O, Singh, Anant, Joshi, Dinesh C., Chiu, Shing-Yan, Mukhtar, Hasan, Syed, Deeba N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200766/
https://www.ncbi.nlm.nih.gov/pubmed/30356079
http://dx.doi.org/10.1038/s41598-018-33879-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200766/
https://www.ncbi.nlm.nih.gov/pubmed/30356079
http://dx.doi.org/10.1038/s41598-018-33879-w

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