Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs

Impairment of the ubiquitin proteasome system has been implicated in Parkinson’s disease. We used positron emission tomography to investigate longitudinal effects of chronic intracerebroventricular exposure to the proteasome inhibitor lactacystin on monoaminergic projections and neuroinflammation. G...

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Detalles Bibliográficos
Autores principales: Lillethorup, Thea P., Glud, Andreas N., Alstrup, Aage K. O., Noer, Ove, Nielsen, Erik H. T., Schacht, Anna C., Landeck, Natalie, Kirik, Deniz, Orlowski, Dariusz, Sørensen, Jens Christian H., Doudet, Doris J., Landau, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200778/
https://www.ncbi.nlm.nih.gov/pubmed/30356172
http://dx.doi.org/10.1038/s41598-018-34084-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200778/
https://www.ncbi.nlm.nih.gov/pubmed/30356172
http://dx.doi.org/10.1038/s41598-018-34084-5

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